FFFold

FFFold is a web application for the force-fields optimization of protein structures predicted by the AlphaFold2 algorithm and deposited in the AlphaFold DB database. The structures are optimized by the PPROpt method, which quality is comparable to the optimization of whole protein structure with constrained α-carbons. The details about the methodology and usage are described in the manual. This website is free and open to all users and there is no login requirement. Source codes are freely available at GitHub.

UniProt code:

Protonate in pH:

FFFold tool is a part of services provided by ELIXIR – European research infrastructure for biological information.
For other services provided by ELIXIR's Czech Republic Node visit www.elixir-czech.cz/services.

Licence conditions in accordance with § 11 of Act No. 130/2002 Coll. The owner of the software is Masaryk University, a public university, ID: 00216224. Masaryk University allows other companies and individuals to use this software free of charge and without territorial restrictions in usual way, that does not depreciate its value. This permission is granted for the duration of property rights. This software is not subject to special information treatment according to Act No. 412/2005 Coll., as amended. In case that a person who will use the software under this licence offer violates the licence terms, the permission to use the software terminates.